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ea0029p1586 | Thyroid (non-cancer) | ICEECE2012

Endocrine bioengineering: reconstruction of a bioartificial thyroid lobe using its natural, three-dimensional (3D) stromal / vascular matrix as a scaffold

Strusi V. , Zini N. , Dallatana D. , Mastrogiacomo S. , Parrilli A. , Giardino R. , Lippi G. , Spaletta G. , Bassoli E. , Gatto A. , Iafisco M. , Sandri M. , Tampieri A. , Toni R.

To test the feasibility of reconstructing ex situ an entire bioartificial thyroid gland suitable for transplantation we have bioengineered a rat thyroid lobe using its decellularized stromal / vascular matrix, eventually 3D recellularized with thyroid stem / precursor cells. Sprague-Dawley male rats (220240 g) were used as thyroid donors, and lobe matrixes obtained by freezing / detergent / enzyme processing. Test matrixes were made electrondense and analyzed by m...

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ea0005p123 | Endocrine Tumours and Neoplasia | BES2003

Preoperative determination of serum thyroglobulin may identify patients with differentiated thyroid cancer who might recur without increased thyroglobulin

Gibelli B , Tradati N , Tredici P , De Cicco C , Bodei L , Sandri M , Chiesa F

Thyroglobulin is generally a reliable marker of recurrent disease in patients with well differentiated thyroid carcinoma. However, some patients have recurrent disease but no increase in serum thyroglobulin. In order to try to identify patients who might recur with no such sign of the disease, we preoperatively assessed thyroglobulin levels in 185 consecutive patients scheduled for primary treatment for well differentiated thyroid carcinoma from June 1997 to May 2002 at the He...

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Endocrine Abstracts

Endocrine bioengineering: reconstruction of a bioartificial thyroid lobe using its natural, three-dimensional (3D) stromal / vascular matrix as a scaffold

Preoperative determination of serum thyroglobulin may identify patients with differentiated thyroid cancer who might recur without increased thyroglobulin

BiosciAbstracts